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SPINLW1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550656

Catalog No. PA550656


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Description

Description

The antibody detects endogenous levels of total EPPIN protein.

Eppin, an epididymal protease inhibitor, belongs to the WFDC family and to the telomeric cluster. The gene encoding the protein is localized to chromosome 20q12-q13 in centromeric and telomeric clusters. It expresses three mRNAs encoding two isoforms of a cystine-rich protein that contains Kunitz-type and WAP-type (four disulfide core) protease inhibitor consensus sequences. The mouse gene lies in a cluster of putative Eppin-like genes on mouse chromosome 2. Following ejaculation, Eppin is bound to semenogelin in seminal plasma and on human spermatozoa. This complex of Eppin and Semenogelin can provide antimicrobial activity for spermatozoa. It can also provide for the preparation and survival of spermatozoa for fertility in the female reproductive tract. Eppin, which is a secreted protein, is expressed in epididymis and testis.
Specifications

Specifications

SPINLW1
Polyclonal
Unconjugated
EPPIN
Liquid
EPPIN
Synthetic peptide corresponding to a region derived from internal residues of human epididymal peptidase inhibitor
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
2.4 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
O95925, Q9DA01
SPINLW1, WAP7, WFDC7
Rabbit
IgG
100 μL
-20°C
Primary
57119, 75526
Documents
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