EPX Mouse anti-Human, Alexa Fluor 594, Clone: EPO104, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234614AF594
DescriptionEPX Monoclonal antibody specifically detects EPX in Human samples. It is validated for Flow Cytometry,ELISA,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen).
|Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen|
|EC 126.96.36.199, eosinophil peroxidase, EPOEPER, EPPEC 1.11.1, EPX-PEN|
|Store at 4°C in the dark.|
|Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen)|
|Alexa Fluor™ 594|
|50 mM sodium borate with 0.05% sodium azide|
|Human eosinophils from a patient with hypereosinophilic syndrome|
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