ER alpha/NR3A1 Mouse anti-Human, Clone: SPM567, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP232965F	Novus Biologicals NBP2329650.02MG	0.02 mg
NBP232965A	Novus Biologicals NBP2329650.1MG	0.1 mg
NBP232965B	Novus Biologicals NBP2329650.2MG	0.2 mg

Description

ER alpha/NR3A1 Monoclonal specifically detects ER alpha/NR3A1 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: ER alpha/NR3A1
• Dilution: Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Accession No.: P03372
• Gene ID (Entrez): 2099
• Immunogen: Recombinant human Estrogen Receptor alpha protein (aa2-185)
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.
• Molecular Weight of Antigen: 67 kDa

• Clone: SPM567
• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Angiogenesis, Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Phospho Specific, Signal Transduction, Transcription Factors and Regulators
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1
• Gene Symbols: ESR1
• Isotype: IgG1 κ
• Purification Method: Protein A purified
• Test Specificity: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.