ER alpha/NR3A1 Mouse, Clone: AER314, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2480120.2MG

Catalog No. NBP248012B

Description

ER alpha/NR3A1 Monoclonal antibody specifically detects Antigen in Bovine, Human, Mouse, Rabbit, Rat samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

• Antigen: ER alpha/NR3A1
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
• Gene Alias: ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG1

• Applications: Flow Cytometry, Immunofluorescence, CyTOF
• Clone: AER314
• Conjugate: Unconjugated
• Formulation: PBS with No Preservative
• Gene Symbols: ESR1
• Immunogen: ER purified from cow uterus
• Quantity: 0.2 mg
• Research Discipline: Angiogenesis, Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Signal Transduction, Transcription Factors and Regulators
• Gene ID (Entrez): 2099
• Target Species: Human, Mouse, Rat, Bovine, Rabbit
• Form: Purified