Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ER Alpha Recombinant Protein, ligand binding domain, GST tag Non-distribution product as customer accommodation.

ER Alpha Recombinant Protein, ligand binding domain, GST tag

Manufacturer:  LIFE TECHNOLOGIES A15677

Catalog No. A15677


Add to cart

Description

Description

This Estrogen Receptor (ER) Alpha Ligand Binding Domain (LBD) is a 62.80 kDa recombinant human protein (amino acids 282-595) expressed as a GST fusion protein in baculovirus-infected insect cells. It was expressed and purified in the absence of exogenous ligands. ER Alpha-LBD recombinant protein binds [3H]-estradiol with sub-nM affinity in hydroxylapatite assays and binds specifically to estrogen response element (ERE) sequences.

ER Alpha-LBD recombinant protein is:
  • Flexible—ideal for ligand binding and coregulator displacement assays developed in-house or partnered with our LanthaScreen™ ER Beta Coactivator Assay or LanthaScreen™ ER Alpha Competitive Binding kits
  • Ready to use—active, purified, and tagged with a GST
  • Convenient—available in bulk sizes

    ER Alpha-LBD recombinant protein is manufactured under the strictest quality parameters. This product is guaranteed for 6 months after purchase. Contact us for bulk quantities or for assistance with other nuclear receptor assay needs, from assay development to library screening and beyond.

    Used in:
    LanthaScreen™ TR-FRET ER Alpha Coactivator Assay Kit
    LanthaScreen™ TR-FRET ER Alpha Competitive Binding Kit

    For bulk reagents, email: !Mad-DiscoveryServices@lifetech.com
  • Specifications

    Specifications

    NP_000116.2
    Pharma and biopharma, target and lead identification and validation
    ER Alpha Recombinant Protein
    80% by SDS-PAGE
    –80°C
    1 Each
    ER Alpha Recombinant Protein
    Insect
    ER Alpha Recombinant Protein
    GST Tag
    0.99mg/mL
    62.8kDa
    8
    25μg
    For research use only. Not for use in diagnostic procedures
    Estrogen receptor 1 (alpha), oestrogen receptor, NR3A1
    Nuclear receptor assay
    Amino acids 282-595
    Human
    Documents
    Provide Content Correction

    The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

    Product Title

    By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

    Cancel Submit

    For Research Use Only. Not for use in diagnostic procedures.