Invitrogen™ ERAB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527155

Catalog No. PIPA527155

Description

Recommended positive controls: HeLaS3, Molt-4, Neuro2A, GL261, PC-12. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Specifications

• Antigen: ERAB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSD17B10
• Gene Alias: 17-beta-HSD 10; 17-beta-hydroxysteroid dehydrogenase 10; 17bHSD10; 17b-HSD10; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3-hydroxyacyl-CoA dehydrogenase type-2; ABAD; AB-binding alcohol dehydrogenase; Ads9; amyloid beta-peptide binding protein; amyloid-beta peptide binding alcohol dehydrogenase; CAMR; DUPXp11.22; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; ERAB; HADH2; HADH2 protein; HCD2; HSD17B10; hydroxyacyl-Coenzyme A dehydrogenase type II; hydroxyacyl-Coenzyme A dehydrogenase, type II; hydroxysteroid (17-beta) dehydrogenase 10; hydroxysteroid 17-beta dehydrogenase 10; hydroxysteroid dehydrogenase 10; MHBD; mitochondrial ribo; Mitochondrial ribonuclease P protein 2; mitochondrial RNas; mitochondrial RNase P protein 2; mitochondrial RNase P subunit 2; MRPP2; MRX17; MRX31; MRXS10; RP3-339A18.2; SCHAD; SDR5C1; Short chain dehydrogenase/reductase family 5C member 1; short chain dehydrogenase/reductase family 5C, member 1; short chain L-3-hydroxyacyl-CoA dehydrogenase; short chain L-3-hydroxyacyl-CoA dehydrogenase type 2; short chain type dehydrogenase/reductase XH98G2; Short-chain type dehydrogenase/reductase XH98G2; type 10 17b-HSD; Type II HADH; XH98G2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15108, 3028, 63864
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O08756, O70351, Q99714
• Gene Symbols: HSD17B10
• Immunogen: Synthetic peptide corresponding to a region within amino acids 201 and 211 of Human ERAB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG