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ERAS Mouse anti-Human, Clone: OTI2C6, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503689

Catalog No. 50-167-4528


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Description

Description

The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.
Specifications

Specifications

ERAS
Monoclonal
Unconjugated
ERAS
Liquid
ERAS
Full length human recombit protein of human ERAS produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunocytochemistry, Immunofluorescence, Western Blot
OTI2C6
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q7Z444
HRAS2, HRASP
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3266
Documents
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