ErbB2/Her2 Antibody (4D5-8 (trastuzumab)) - Chimeric - Azide and BSA Free, Novus Biologicals™

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP2526390.025MG

Catalog No. NBP25263925

Description

ErbB2/Her2 Monoclonal specifically detects ErbB2/Her2 in Human samples. It is validated for Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.

Specifications

• Antigen: ErbB2/Her2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% Proclin 300. with 0.02% Proclin 300
• Gene Symbols: ERBB2
• Immunogen: A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
• Quantity: 0.025 mg
• Research Discipline: Breast Cancer, Cancer, Cellular Markers, Core ESC Like Genes, Oncogenes, Protein Kinase, Stem Cell Markers, Tumor Suppressors
• Gene ID (Entrez): 2064
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry, ELISA, Immunohistochemistry, CyTOF
• Clone: 4D5-8 (trastuzumab)
• Dilution: Flow Cytometry 1:10 - 1:1000, ELISA 1:100 - 1:2000, Immunohistochemistry 1:10 - 1:500, CyTOF-ready
• Gene Alias: CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
• Host Species: Rabbit
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG