ERCC1 Mouse anti-Human, Clone: OTI6H7, lyophilized, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene CF805691

Catalog No. 50-166-7536

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3 ft. of the DNA lesion while the ERCC1-XPF complex makes the 5 ft. incision.

Specifications

• Antigen: ERCC1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ERCC1
• Format: Lyophilized
• Gene Symbols: ERCC1
• Immunogen: Full length human recombit protein of human ERCC1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI6H7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P07992
• Gene Alias: COFS4, RAD10, UV20
• Host Species: Mouse
• Isotype: IgG2a
• Quantity: 100 μg
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 2067