ERCC1 Mouse anti-Human, Clone: OTI6H7, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF805691
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOThe mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3 ft. of the DNA lesion while the ERCC1-XPF complex makes the 5 ft. incision.
|Full length human recombit protein of human ERCC1 produced in HEK293T cell.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 8% trehalose and no preservative; pH 7.3|
|COFS4, RAD10, UV20|
|-20° C, Avoid Freeze/Thaw Cycles|
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