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ERI1 Mouse anti-Human, Rat, Clone: OTI1B3, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA504134

Catalog No. 50-167-4883


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Description

Description

RNA exonuclease that binds to the 3 ft.-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2 ft. and 3 ft.-hydroxyl groups at the last nucleotide of the histone 3 ft.-end is required for efficient degradation of RNA substrates. Also able to degrade the 3 ft.-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5 ft.-ACCCA-3 ft. sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3 ft.-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Specifications

Specifications

ERI1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q5FVR4, Q8IV48
3′HEXO, HEXO, THEX1
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
361159, 90459
Immunohistochemistry (Paraffin), Western Blot
OTI1B3
Unconjugated
ERI1
Liquid
ERI1
Full length human recombit protein of human ERI1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human, Rat
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