MAPK4 Mouse anti-Human, Clone: OTI2F4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526218
DescriptionProtein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|ERK3, Erk4, PRKM4, p63MAPK, ERK-4, Erk3-related, MAP kinase 4, MAP kinase isoform p63, MAPK 4, extracellular signal-regulated kinase 4, p63-MAPK|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of MAPK4 produced in HEK293T cell|
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