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ERN2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA513921

Catalog No. PIPA513921


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Description

Description

ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
Specifications

Specifications

ERN2
Polyclonal
Unconjugated
Q76MJ5, Q9Z2E3
ERN2
KLH conjugated synthetic peptide between 39-72 amino acids from the N-terminal region of human ERN2
400 μL
Primary
Human, Mouse
Antibody
IgG
Western Blot
2 mg/mL
ERN2
Serine/threonine-protein kinase/endoribonuclease IRE2 [Precursor]; Inositol-requiring 2; hIRE2p; IRE1b; Ire1-beta; Endoplasmic reticulum-to-nucleus signaling 2; ERN2; IRE2;
Rabbit
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
10595, 26918
-20° C, Avoid Freeze/Thaw Cycles
Liquid
SDS
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