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ERp72 Rabbit anti-Human, Mouse, Alexa Fluor® 488, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1007A488

Catalog No. PIPA1007AX


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Description

Description

PA1007A488 detects ERp72 protein in human and mouse samples. The PA1007A488 immunogen is a synthetic peptide corresponding to residues K(629) F I E E H A T K L S R T K E E L(645) of human ERp72. This peptide (Cat. No. PEP-223) is available for use in neutralization and control experiments.

ERp72 is an endoplasmic reticulum luminal protein that is both a stress protein and a member of the protein disulfide isomerase family of proteins. Sequence analysis of ERp72 shows that it shares sequence identity with PDI (protein disulphide isomerase) at three discrete regions, as well as containing the ER retention signal KEEL at its C-terminus. ERp72 is shown to have three copies of sequence believed to be CGHC-containing active sites, which are also found in PDI. These CGHC sites are critical sites that are involved in the protein disulphide isomerization process. These results suggest that ERp72 is a newly described member of the family of CGHC-containing proteins that functions as a molecular chaperone.
Specifications

Specifications

ERp72
Polyclonal
Alexa Fluor™ 488
PDIA4
Liquid
PDIA4
Synthetic peptide corresponding to residues K(629) F I E E H A T K L S R T K E E L(645) of humna ERp72
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
P13667, P08003
AI987846, Erp72, ERP72, ERp-72, ERP70, Cai
Rabbit
IgG
50 μL
4° C, store in dark, DO NOT FREEZE!
Primary
12304, 9601
Documents
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