ERR-alpha Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Supplier:  Active Motif 61048

Catalog No. 50-199-3089

Description

Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor. This protein binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3' can bind to the medium-chain acyl coenzyme a dehydrogenase (mcad) response element nrre-1 and may act as an important regulator of mcad promoter. Studies have shown that ERR1 functions a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for the ERR1 is NR3B1.

Specifications

• Antigen: ERR-alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ESRRA
• Gene Alias: ERR alpha; ERR1; ERRa; ERRalpha; ERR-alpha; Errra; ESRL1; ESRRA; estrogen receptor related 1; Estrogen receptor-like 1; estrogen related receptor alpha; estrogen related receptor, alpha; estrogen-related nuclear receptor alpha; Estrogen-related receptor alpha; estrogen-related receptor, alpha; Estrra; HERR1; Nr3b1; Nuclear receptor subfamily 3 group B member 1; orphan nuclear receptor; Steroid hormone receptor ERR1; Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2101
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: Lot-Specific
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: P11474
• Gene Symbols: ESRRA
• Immunogen: This ERR-alpha antibody was raised against a peptide within the C-terminal region of human ERR alpha.
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG