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ESRRB Monoclonal Antibody (OTI12B7), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA805646

Encompass_Preferred

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Catalog No. 50-168-0791


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Description

Description

ESRRB (steroid hormone receptor ERR2) plays a role in maintaice of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Upon FGF signaling pathway activation ESRRB interacts with KDM1A by directly binding to enhancer sites of ELF5 and EOMES and activates their transcription leading to self-renewal of trophoblast stem cells. ESSRB also regulates expression of multiple rod-specific genes and is required for survial of this cell type. Defects in the gene can cause deafness, autosomal recessive, 35 (DFNB35).
Specifications

Specifications

ESRRB
Monoclonal
Unconjugated
ESRRB
DFNB35, ERR2, ERRb, ESRL2, NR3B2
Mouse
Affinity Chromatography
RUO
2103
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
OTI12B7
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
O95718
ESRRB
Human recombit protein fragment corresponding to amino acids 1-252 of human ESRRB produced in E.coli.
100 μL
Primary
Human
Antibody
IgG2b
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