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Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-10, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in western blotting, immunoprecipitation, gel supershift and  chromatin precipitation experiments.

Specifications

Antigen Estrogen Receptor Ab-10
Clone TE111.5D11
Applications Immunoprecipitation
Classification Monoclonal
Format Concentrated
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Products 8
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS315B
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Thermo Scientific™
MS315B
200μg/mL Biotin 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS315B0
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Thermo Scientific™
MS315B0
200μg/mL Biotin 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS315B1
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Thermo Scientific™
MS315B1
200μg/mL Biotin 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS315P
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Thermo Scientific™
MS315P
200μg/mL Unconjugated 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS315P0
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Thermo Scientific™
MS315P0
200μg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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MS315P1
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Thermo Scientific™
MS315P1
200μg/mL Unconjugated 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS315P1ABX
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Thermo Scientific™
MS315P1ABX
1mg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS315PABX
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Thermo Scientific™
MS315PABX
1mg/mL Unconjugated 200μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in western blotting, immunoprecipitation, gel supershift and chromatin precipitation experiments with Thermo Scientific™ Estrogen Receptor Ab-10, Mouse Monoclonal Antibody.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: TE111.5D11

Isotype: IgG1

Species Reactivity: Human, Cow, Pig, Dog, Mouse, Rat, Sheep, Rabbit, Hamster and Chicken. Others not known.

Epitope: aa 302-553

Immunogen: 35 kDa, C-terminal fragment (aa 302-595) of human ER expressed in E. coli

Molecular Weight: 67 kDa

Positive Control: T47D cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native and denatured)
  • Gel Supershift
  • Blocks Binding of Estrogen to ER
  • Chromatin Precipitation

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Estrogen Receptor Ab-10
Immunoprecipitation
Concentrated
RUO
Primary
IgG1
TE111.5D11
Monoclonal
Murine
Steroids Hormones and Growth Factors
35kDa, C-terminal fragment (aa 302-595) of human ER expressed in E. coli
SDS
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