Thermo Scientific Lab Vision Estrogen Receptor Ab-17, Rabbit Polyclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.
Manufacturer: Thermo Scientific RB1521P
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific Estrogen Receptor Ab-17, Rabbit Polyclonal Antibody.ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Host Species: Rabbit
Species Reactivity: Human, Rat, Mouse, Rabbit, Sheep, Pig and Cow. Others not known.
Immunogen: A synthetic peptide from the N-terminus of human estrogen receptor, α protein
Molecular Weight: 67 kDa
Positive Control: MCF-7 cells, Breast CA
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
USA: RUO; Int'l: RUO
|Estrogen Receptor Ab-17|
|A synthetic peptide from the N-terminus of human estrogen receptor, alpha protein|
|Steroids Hormones and Growth Factors|
|Bovine, Human, Murine, Porcine, Rabbit, Rat|
|Immunoprecipitation, Western Blot|
|Purified Ab with BSA and Azide|
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