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Thermo Scientific™ Lab Vision™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ RM9101S1

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Catalog No. RM9101S1


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Description

Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Clone: SP1

Isotype: IgG

Species Reactivity: Human, Mouse and Hamster. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor

Molecular Weight: 67 kDa

Positive Control: Breast CA, MCF-7 cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence (Not verified)
  • Flow Cytometery (Not verified)
Specifications

Specifications

Estrogen Receptor (SP1)
Monoclonal
Unconjugated
Concentrated
Synthetic peptide derived from C-terminal of human estrogen receptor
500μL
Steroids Hormones and Growth Factors
Primary
Hamster, Human, Murine
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
SP1
Culture Supernatant with Azide
Rabbit
IgG
IVD
Primary
Monoclonal
SDS
Documents
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