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ETF1 Mouse anti-Human, Clone: OTI2E3, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA502891

Catalog No. 50-167-3894


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Description

Description

Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA, a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs, which are not codon specific and do not recognize codons, stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes, both class 1 RFs, RF1 and RF2, recognize UAA; however, UAG and UGA are decoded specifically by RF1 and RF2, respectively. In eukaryotes, eRF1, or ETF1, the functional counterpart of RF1 and RF2, functions as an omnipotent RF, decoding all 3 stop codons.
Specifications

Specifications

ETF1
Monoclonal
0.97 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P62495
D5S1995, ERF, ERF1, RF1, SUP45L1, TB3-1
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2107
Flow Cytometry, Western Blot
OTI2E3
Unconjugated
ETF1
Liquid
ETF1
Full length human recombit protein of human ETF1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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