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EXD1 Mouse anti-Human, Clone: OTI3H7, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA502158

Catalog No. 50-167-3237


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Description

Description

EXD1 is an RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease.
Specifications

Specifications

EXD1
Monoclonal
0.73 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q8NHP7
EXDL1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
161829
Flow Cytometry, Western Blot
OTI3H7
Unconjugated
EXD1
Liquid
EXD1
Full length human recombit protein of human EXD1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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