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EXD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 173131AP

Catalog No. 50-173-1502


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Description

Description

This antibody can recognize all these three isoforms.

EXD1 is an RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease.
Specifications

Specifications

EXD1
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8CDF7, Q8NHP7
EXD1, EXDL1
Rabbit
IgG
150 μL
-20°C
Primary
161829, 241624, 311334
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
EXD1
Liquid
Exd1
EXD1 Fusion Protein Ag11282
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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