Invitrogen™ EXOC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596980

Catalog No. PIPA596980

Description

Immunogen sequence: MSRSRQPPLV TGISPNEGIP WTKVTIRGEN LGTGPTDLIG LTICGHNCLL TAEWMSASKI VCRVGQAKND KGDIIVTTKS GGRGTSTVSF KLLKPEKIGI LDQSAVWVDE MNYYDMRTDR NKGIPPLSLR PANPLGIEIE KSKFSQKDLE MLFHGMSADF TSENFSAAWY LIENHSNTSF EQLKMAVTNL KRQANKKSEG SLAYVKGGLS TFFEAQDALS; Positive Samples: A-549, MCF7, HeLa, Mouse lung, Rat brain.

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts.

Specifications

• Antigen: EXOC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Exoc2
• Gene Alias: 2410030I24Rik; AI648199; Exoc2; Exocyst complex component 2; Exocyst complex component 2-like protein; exocyst complex component Sec5; rSec5; Sec5; SEC5 homolog; Sec5 protein; Sec5l1; SEC5-like 1; Sec5p
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171455, 55770, 66482
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Concentration: 0.95 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O54921, Q96KP1, Q9D4H1
• Gene Symbols: Exoc2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human EXOC2 (NP_0607733).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG