F11R Mouse anti-Human, Clone: OTI3H3, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA506017
DescriptionCD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintece of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
|Full length human recombit protein of human F11R produced in HEK293T cell.|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1|
|-20° C, Avoid Freeze/Thaw Cycles|
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