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F4/80 Rat anti-Mouse, eFluor 506, Clone: BM8, eBioscience™ Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  LIFE TECHNOLOGIES 69480182

Encompass

Catalog No. 69-480-182


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Description

Description

The BM8 MAb reacts with mouse F4/80 antigen, an approximately 160 kDa surface receptor. It belongs to the EGF-TM7 family of proteins. As such it contains seven EGF-like domains on its extracellular N-terminus, seven transmembrane spanning sequences, and an intracellular C-terminal domain showing homology to other TM7 superfamily members. The F4/80 antigen is expressed by a majority of mature macrophages and is one of the best markers for this population of cells. However, other cell types, such as peritoneal eosinophils, Langerhans cells, and some other dendritic cell subtypes, have been reported to express this antigen as well. Expression of F4/80 commences during early myeloid development in vivo and can be upregulated on BM cells stimulated in vitro with M-CSF. Some populations of macrophages, especially in the lymphoid microenvironment, may be devoid of F4/80.

F4/80 Monoclonal antibody specifically detects F4/80 in Mouse samples. It is validated for Flow Cytometry
Specifications

Specifications

F4/80
Flow Cytometry
BM8
eFluor 506
ADGRE1
ADGRE1; adhesion G protein-coupled receptor E1; Cell surface glycoprotein F4/80; DD7A5-7; egf-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; EMR1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
13733
Liquid
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q61549
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
SDS
Documents
Product Certifications
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