Invitrogen™ F7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109703

Catalog No. PIPA5109703

Description

Immunogen sequence: RNLIAVLGEH DLSEHDGDEQ SRRVAQVIIP STYVPGTTNH DIALLRLHQP VVLTDHVVPL CLPERTFSER TLAFVRFSLV SGWGQLLDRG ATALELMVLN VPRLMTQDCL QQSRKVGDSP NITEYMFCAG YSDGSKDSCK GDSGGPHATH YRGTWYLTGI V.

Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.

Specifications

• Antigen: F7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: F7
• Gene Alias: AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14068, 2155, 260320
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.86 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P08709, P70375, Q8K3U6
• Gene Symbols: F7
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-400 of human F7 (NP_062562.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG