Factor V Heavy chain Monoclonal Antibody (B10), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA110827

Catalog No. 01-671-855

Description

MA1-10827 detects Factor V, heavy chain, from human samples. MA1-10827 has been successfully used in ELISA and immunohistochemistry applications. The MA1-10827 immunogen is purified human Factor V.

This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.

Specifications

• Antigen: Factor V Heavy chain
• Classification: Monoclonal
• Concentration: 0.65 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P12259
• Gene Symbols: F5
• Immunogen: Purified human Factor V.
• Quantity: 250 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry
• Clone: B10
• Conjugate: Unconjugated
• Gene: F5
• Gene Alias: activated protein c cofactor; Coagulation factor V; coagulation factor V (proaccelerin, labile factor); Coagulation factor V heavy chain; coagulation factor V jinjiang A2 domain; Coagulation factor V light chain; F5; factor V Leiden; FVL; PCCF; Proaccelerin, labile factor; RPRGL1; THPH2
• Host Species: Mouse
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 2153
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid