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Thermo Scientific™ Lab Vision™ Factor XIII A Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Factor XIII A Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ MS1237R7

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Catalog No. MS1237R7


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Description

Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Factor XIII A Ab-1, Mouse Monoclonal Antibody.

Detect factor XIII in both reduced and non-reduced forms. This abtibody does not react with human Factor XIII B-chain or human Factor XII. Factor XIII is a Β-globulin found in plasma and is composed of two subunits. Factor XIII-A is the catalytic subunit and is a dimer of M.W. 160 kDa. Factor XIII is present in plasma as an alpha2Β2 heterodimer (M.W. 320 kDa); whereas in platelets, only the α2 unit exists. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system. Factor XIII has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans.

Host Species: Mouse

Clone: AC-1A1

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant protein corresponding to A-subunit of coagulation Factor XIII

Molecular Weight: 160 kDa (unreduced dimmer); 80 kDa (reduced monomer)

Positive Control: Recombinant human Factor XIII A-subunit; Capillary hemangioma, dermatofibroma and placenta

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
Specifications

Specifications

Factor XIII A Ab-1
Monoclonal
Unconjugated
Prediluted
Recombinant protein corresponding to A-subunit of coagulation Factor XIII
7mL
Hematopoietic
Primary
Human
Immunohistochemistry (Paraffin), Western Blot
AC-1A1
Ready-to-use for IHC (UVLP)
Murine
IgG2a kappa
IVD
Primary
Monoclonal
SDS
Documents
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