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FAK Inhibitor 14, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
FAK Inhibitor 14 is a selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. FAK Inhibitor 14 prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. FAK Inhibitor 14 exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo.
Specifications
Quantity | 50 mg |
Formula Weight | 284.01 |
Percent Purity | >98% |
Chemical Name or Material | FAK Inhibitor 14 |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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