Invitrogen™ FAM65A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552228

Catalog No. PIPA552228

Description

Immunogen sequence: HALESFSFLN EDEDEDNDVP GDRPPSSPEA GAEDSIDSPS ARPLSTGCPA LDAALVRHLY HCSRLLLKLG TFGPLRCQEA WALERLLREA RVLEAVCEFS RRWEIPASSA QEVVQFS Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.

Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt].

Specifications

• Antigen: FAM65A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RIPOR1
• Gene Alias: 2310066E14Rik; AI837433; Fam65a; family with sequence similarity 65 member A; family with sequence similarity 65, member A; FLJ13725; Kiaa1930; protein FAM65A; Rho family-interacting cell polarization regulator 1; RIPOR1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79567
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6ZS17
• Gene Symbols: RIPOR1
• Immunogen: Recombinant protein corresponding to Human FAM65A. Recombinant protein control fragment (Product #RP-100912).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG