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FAM89B Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550410

Catalog No. PA550410


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Description

Description

The antibody detects endogenous levels of total FAM89B protein.

Mtvr1 (mammary tumor virus receptor homolog 1), also known as FAM89B (family with sequence similarity 89, member B), is a 176 amino acid protein that exists as two alternatively spliced isoforms. Belonging to the FAM89 family, Mtvr1 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms ft. tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
Specifications

Specifications

FAM89B
Polyclonal
Unconjugated
FAM89B
Liquid
FAM89B
Full length fusion protein of Human FAM89B
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q8N5H3
MTVR1
Rabbit
IgG
100 μL
-20°C
Primary
23625
Documents
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