FANCD2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 240061AP
The antibody recognize both un-phospho and phospho-Ser(330) of FANCD2.Fanconi anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANCD2, targeting nuclear foci containing the BRCA1 protein.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|FA D2, FA4, FACD, FAD, FAD2, FANCD, FANCD2, Protein FACD2|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Antigen Affinity Chromatography|
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