Invitrogen™ FAPP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567238

Catalog No. PIPA567238

Description

Immunogen sequence: TSELLYRTPPG SPQLAMLKSS KMKHPIIPIH NSLERQMELS TCENGSLNME INGEEEILMK NKNSLYLKSA EIDCSISSEE NTDDNITVQG EIMK Highest antigen sequence identity to the following orthologs - mouse 85%, rat 78%.

Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.

Specifications

• Antigen: FAPP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLEKHA8
• Gene Alias: 6330400G01; AA517676; BC052360; FAPP2; Fapp-2; hFAPP2; MGC3358; PH domain-containing family A member 8; phosphatidylinositol-four-phosphate adapter protein 2; phosphoinositol 4-phosphate adapter protein 2; pleckstrin homology domain containing A8; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; pleckstrin homology domain-containing family A member 8; PLEKHA8; RGD1563940; Serologically defined breast cancer antigen NY-BR-86
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84725
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96JA3
• Gene Symbols: PLEKHA8
• Immunogen: Recombinant Human FAPP2. Recombinant protein control fragment (Product #RP-107874).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov