FBXO5 Mouse anti-Human, Clone: EMI1/1176, Abnova™
Mouse monoclonal antibody raised against partial recombinant human FBXO5.
Manufacturer: Abnova Corporation MAB13276
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
|Mouse monoclonal antibody raised against partial recombinant human FBXO5.|
|In 1mM PBS.|
|Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing.
|Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (1-2 ug/mL) The optimal working dilution should be determ|
|Recombinant protein corresponding to 203 residues around amino acids 1-250 of human FBXO5.|
|Protein A/G purification|
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