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FBXO8 Mouse anti-Human, Clone: OTI3C5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526888

Catalog No. PIMA526888


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Description

Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Specifications

Specifications

FBXO8
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9NRD0
FBS, FBX8, F-box only protein 8, F-box protein Fbx8, F-box/SEC7 protein FBS
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
26269
Immunohistochemistry (Paraffin), Western Blot
OTI3C5
Unconjugated
FBXO8
Liquid
FBXO8
Human recombit protein fragment corresponding to amino acids 1-231 of FBXO8 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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