FBXW5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 183211AP
DescriptionThis gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|Q4KLI9, Q969U6, Q9QXW2|
|Fbw5, FBXW5, RP11 229P13.10|
|30839, 362081, 54461|
|Immunohistochemistry (Paraffin), Western Blot|
|FBXW5 Fusion Protein Ag13163|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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