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FBXW7 Monoclonal Antibody (OTI10B9), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Supplier: OriGene TA802871
Description
Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of maligcies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.Specifications
| FBXW7 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q969H0 | |
| FBXW7 | |
| Human recombit protein fragment corresponding to amino acids 1-354 of human FBXW7 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI10B9 | |
| Unconjugated | |
| FBXW7 | |
| AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 55294 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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