FBXW7 Mouse anti-Human, Clone: OTI4C11, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF802883
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOCyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of maligcies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.
|Human recombit protein fragment corresponding to amino acids 1-354 of human FBXW7 produced in E.coli.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 8% trehalose and no preservative; pH 7.3|
|AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4|
|-20° C, Avoid Freeze/Thaw Cycles|
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