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Fc gamma RIIIA/CD16a, Rabbit anti-Human,Baboon,Cynomolgus Monkey,Chimpanzee,Rhesus Monkey, Clone: 3G8, Novus Biologicals™
Rabbit Monoclonal Antibody
$242.00 - $545.00
Specifications
Antigen | Fc gamma RIIIA/CD16a |
---|---|
Clone | 3G8 |
Concentration | 1 mg/mL |
Dilution | Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Surface Plasmon Resonance, Block/Neutralize |
Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Blocking Assay |
Description
Fc gamma RIIIA/CD16a Monoclonal specifically detects Fc gamma RIIIA/CD16a in Human, Chimpanzee, Baboon, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Surface Plasmon Resonance, Block/Neutralize.Specifications
Fc gamma RIIIA/CD16a | |
1 mg/mL | |
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Blocking Assay | |
Unconjugated | |
Rabbit | |
Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers | |
PBS | |
2214 | |
3G8 was prepared by immunizing mice with human PMN (polymorphonuclear leukocytes) cells. | |
Primary | |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
3G8 | |
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Surface Plasmon Resonance, Block/Neutralize | |
Monoclonal | |
Purified | |
RUO | |
Human, Baboon, Cynomolgus Monkey, Chimpanzee, Rhesus Monkey | |
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA | |
FCGR3A | |
IgG κ | |
Protein A purified | |
3G8 binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity). |
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