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Fcμ Receptor Mouse anti-Mouse, PE, Clone: MM3, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 566030

Catalog No. BDB566030

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The MM3 monoclonal antibody specifically binds to the Fc receptor for IgM (Fcμ Receptor, FcμR), which is also known as Fas apoptosis inhibitory molecule 3 (Faim3) or Toso. The Fcμ Receptor is a transmembrane sialoglycoprotein that is encoded by Fcmr (Fc fragment of IgM receptor). This receptor contains an extracellular Ig-like domain that is homologous to two other IgM-binding receptors, the Fc receptor for IgM and polymeric IgA (Fc /μR) and the polymeric Ig receptor (pIgR). Unlike these receptors, the Fcμ Receptor exhibits exclusive binding specificity for the Fc region of IgM. Fcμ Receptor expression is restricted to B lymphocytes. Although expressed by all mature B cell subsets, Fcμ Receptor levels are transiently downregulated by germinal center B cells. This receptor is not expressed by T cells, NK cells, dendritic cells, or myeloid cells.

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
Specifications

Specifications

Fcμ Receptor
0.2mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Fcmr, FcmuR, Fcμ Receptor, FcμR, Faim3, Toso
Mouse FcμR Transfected Cell Line
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
RUO
Primary
Murine
MM3
PE
Affinity Purified
Murine
Mouse IgG1, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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