FCER2 Mouse anti-Human, Clone: OTI9B6, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF801830
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOCD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
|Human recombit protein fragment corresponding to amino acids 48-321 of human FCER2 produced in SF9 cell.|
|PBS with 8% trehalose and no preservative; pH 7.3|
|BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF|
|-20° C, Avoid Freeze/Thaw Cycles|
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