Invitrogen™ FEM1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566607

Catalog No. PIPA566607

Description

Immunogen sequence: VEYLIQEQPGQ EQVAGGEAQP GLPQEDPSTS QGCAQPQGAP CCSSSPEEPL NGESYESCCP TSREAAVEA Highest antigen sequence identity to the following orthologs - mouse 57%, rat 56%.

FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.

Specifications

• Antigen: FEM1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FEM1A
• Gene Alias: AW611390; DKFZp762M136; EPRAP; fem-1 homolog A; fem-1 homolog a (C. elegans); Fem1a; Fem1aa; FEM1a-A; FEM1-alpha; FEM1-alpha-A; feminization 1 homolog a; feminization 1 homolog a (C. elegans); prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; protein fem-1 homolog A-A; similar to fem-1 homolog a (C.elegans)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55527
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BSK4
• Gene Symbols: FEM1A
• Immunogen: Recombinant Human FEM1A. Recombinant protein control fragment (Product #RP-107265).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov