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FERMT3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 181311AP

Catalog No. 50-173-2003

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This antibody works well in WB, IHC and IF applications.

The three KINDLINs are a novel family of focal adhesion proteins, localizing to integrin adhesion sites. The KINDLIN proteins are composed of a centrally located FERM domain interrupted by a pleckstrin homology (PH) domain. KINDLIN1 and KINDLIN2 have been shown to play an essential role in integrin-mediated adhesion and spreading. In contrast to the widely expressed KINDLIN1 and KINDLIN2, KINDLIN3 is restricted to hematopoietic cells and is particularly abundant in megakaryocytes and platelets. Several reports describe a transcriptional misregulation of KINDLINs in various types of cancer. A recent study demonstrates that KINDLIN3 is essential for platelet integrin activation and subsequent integrin outside-in signaling, suggesting it may serve as a potential target for the design of therapeutics aimed at specifically disrupting integrin activation in platelets and leukocytes.


0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q86UX7, Q8K1B8
Fermitin family homolog 3, FERMT3, KIND3, Kindlin 3, MIG 2, MIG2 like protein, MIG2B, Unc 112 related protein 2, UNC112C, URP2, URP2SF
150 μL
108101, 309186, 83706
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
FERMT3 Fusion Protein Ag12713
Antigen Affinity Chromatography
Human, Mouse, Rat
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