Tocris Ferrostatin 1
Selective inhibitor of erastin induced ferroptosis
Manufacturer: Tocris 5180/50
DescriptionSelective inhibitor of erastin induced ferroptosis (EC50 = 60nM). Specifically inhibits Ras selective lethal compound -induced death, but not cell death induced by other oxidative lethal compounds and apoptosis-inducing agents. Inhibits ferroptosis in cancer cells; also inhibits glutamate-induced cell death in organotypic rat brain slices. Prevents erastin induced accumulation of cytosolic and lipid reactive oxygen species.
- Chemical Name: Ethyl 3-amino-4-(cyclohexylamino)benzoate
- Formula: C15H22N2O2
- CAS Number: 347174-05-4
- Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
- Purity: >98
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