FES Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549781
The antibody detects endogenous levels of total FES protein.This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintece of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.
|Synthesized peptide derived from internal of human FES.|
|Antigen affinity chromatography|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.4|
|Proto-oncogene tyrosine-protein kinase Fes/Fps, EC 220.127.116.11, C-Fes, FES, FPS|
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