FIG4 Mouse anti-Human, Mouse, Rat, Clone: S202-7, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527648
DescriptionThe PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/multivesicular bodies (MVB) transport intermediates from early endosomes.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.4|
|Polyphosphoinositide phosphatase, 5-bisphosphate 5-phosphatase, Fig4, KIAA0274, Sac3, Phosphatidylinositol 3, Phosphatidylinositol 3,5 bisphosphate 5 phosphatase, SAC domain containing protein 3, SAC domain-containing protein 3, SAC3|
|103199, 309855, 9896|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Fusion protein amino acids 688-907 (C-terminus) of mouse Sac3. Rat: 95% identity (203/220 amino acids identical). Human: 91% identity (201/220 amino acids identical)|
|Human, Mouse, Rat|
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