Filensin Mouse anti-Human, Clone: OTI1F4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526640
DescriptionMore than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|CP115, CP94, LIFL-H, cytoskeletal protein, 115 KD, filensin, lens fiber cell beaded-filament structural protein CP 115, lens intermediate filament-like heavy|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 405-665 of BFSP1 produced in E.coli|
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