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FK 866 hydrochloride (Visfatin), Tocris Bioscience™
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Quantity:
10mg
Description
Non-competitive and potent inhibitor of NAMPT (nicotinamide phosphoribosyltransferase, PBEF1) (Ki = 0.3 nM); inhibits NAD biosynthesis. Induces delayed cell death by apoptosis in HepG2 human liver carcinoma cells (IC50 ∽1 nM). Induces apoptosis in four different neuroblastoma cell lines; also induces autophagy in SH-SY5Y cells. Potentiates the cytotoxic effects induced by etoposide (Cat. No. 1226) and cisplatin (Cat. No. 2251).
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Specifications
Quantity | 10mg |
Formula Weight | 427.97 |
Chemical Name or Material | FK 866 hydrochloride (Visfatin) |
Safety and Handling
Recommended Storage : Store at -20°C