Tocris™ FLI 06

Inhibitor of Notch signaling

Manufacturer: Tocris™ 5172/50

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Catalog No. 51-725-0

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For Research Use Only


    Molecular Weight 438.52
    Quantity 50mg
    Inhibitors FLI 06
    Purity >99
    Product Type FLI 06

    Inhibitor of Notch signaling (EC50 = 2.3µM). Disrupts Notch trafficking and processing. Reduces amyloid β secretion. Changes the maturation and abolishes shredding of APP. Inhibits ER exporting and converts tubular ER to sheets.

    • Chemical Name: Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate
    • Formula: C25H30N2O5
    • CAS Number: 313967-18-9
    • Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
    • Purity: >99

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