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Tocris Bioscience™ FLI 06

Inhibitor of Notch signaling; disrupts Notch trafficking and processing

Manufacturer:  Tocris Bioscience™ 5172/10

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Catalog No. 51-721-0

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Inhibitor of Notch signaling (EC50 = 2.3 μM). Disrupts Notch trafficking and processing. Reduces amyloid β secretion. Changes the maturation and abolishes shredding of APP. Inhibits ER exporting and converts tubular ER to sheets.


FLI 06
FLI 06
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