Tocris FLI 06
Inhibitor of Notch signaling
Manufacturer: Tocris 5172/10
DescriptionInhibitor of Notch signaling (EC50 = 2.3µM). Disrupts Notch trafficking and processing. Reduces amyloid β secretion. Changes the maturation and abolishes shredding of APP. Inhibits ER exporting and converts tubular ER to sheets.
- Chemical Name: Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate
- Formula: C25H30N2O5
- CAS Number: 313967-18-9
- Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
- Purity: >99
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